![]() ![]() ![]() Advances in Experimental Medicine and Biology 2021 1330 de Koning, C Tao, W Lacna, A van Veghel, K Horwitz, ME Sanz, G Jagasia, MH Wagner, JE Stiff, PJ Hanna, R Cilloni, D Valcárcel, D Peled, T Galamidi Cohen, E Goshen, U Pandit, A Lindemans, CA Jan Boelens, J Nierkens, S Lymphoid and myeloid immune cell reconstitution after nicotinamide-expanded cord blood transplantation. British journal of haematology 2021 Drakes, ML Stiff, PJ Ovarian Cancer: Therapeutic Strategies to Overcome Immune Suppression. Transplantation and cellular therapy 2021 Riedell, PA Hamadani, M Ahn, KW Litovich, C Brunstein, CG Cashen, AF Cohen, JB Epperla, N Hill, BT Im, A Inwards, DJ Lister, J McCarty, JM Ravi Kiran Pingali, S Shadman, M Shaughnessy, P Solh, M Stiff, PJ Vose, JM Kharfan-Dabaja, MA Herrera, AF Sauter, CS Smith, SM Effect of time to relapse on overall survival in patients with mantle cell lymphoma following autologous haematopoietic cell transplantation. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2021 Riedell, PA Hamadani, M Ahn, KW Litovich, C Murthy, GSG Locke, FL Brunstein, CG Merryman, RW Stiff, PJ Pawarode, A Nishihori, T Kharfan-Dabaja, MA Herrera, AF Sauter, CS Smith, SM Outcomes and Utilization Trends of Front-Line Autologous Hematopoietic Cell Transplantation for Mantle Cell Lymphoma. Blood 2021 Desai, PM Brown, J Gill, S Solh, MM Akard, LP Hsu, JW Ustun, C Andreadis, C Frankfurt, O Foran, JM Lister, J Schiller, GJ Wieduwilt, MJ Pagel, JM Stiff, PJ Liu, D Khan, I Stock, W Kambhampati, S Tallman, MS Morris, L Edwards, J Pusic, I Kantarjian, HM Mamelok, R Wong, A Van Syoc, R Kellerman, L Panuganti, S Mandalam, R Abboud, CN Ravandi, F Open-Label Phase II Prospective, Randomized, Controlled Study of Romyelocel-L Myeloid Progenitor Cells to Reduce Infection During Induction Chemotherapy for Acute Myeloid Leukemia. Exogenous sialic acid content, in concert with other serum factors, plays a role in determining the capsular size in GBS.Publications Horwitz, ME Stiff, PJ Cutler, CS Brunstein, CG Hanna, R Maziarz, RT Rezvani, AR Karras, NA McGuirk, JP Valcarcel, D Schiller, GJ Lindemans, CA Hwang, WY Koh, LP Keating, AK Khaled, Y Hamerschlak, N Frankfurt, O Peled, T Segalovich, I Blackwell, B Wease, S Freedman, LS Galamidi-Cohen, E Sanz, GF Omidubicel Versus Standard Myeloablative Umbilical Cord Blood Transplantation: Results of a Phase III Randomized Study. The concentration of bacterial cell sialic acid was directly correlated with the sialic acid content of the serum. When grown in serum this pool was reduced to a level similar to that in other strains. ![]() Interestingly, while there was little difference between the intracellular sialic levels of most isolates, the sialic acid level of COH31-15 grown in THB was over 100% higher than that of any other isolate. ![]() We measured the intracellular levels of sialic acid for a variety of GBS serotype III isolates. Several unique proteins were produced on serum growth and there was both up- and down-regulation of other proteins. A significant change in membrane composition was found during growth in human serum. We isolated cytoplasmic membranes from GBS and separated the component membrane proteins by polyacrylamide gel electrophoresis. A Group B Streptococcus Type III (GBS) mutant which, when grown in Todd Hewitt broth (THB), does not produce any detectable capsule, produced a clearly visible polysaccharide capsule when grown in human serum. ![]()
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